One of the emerging applications of clinical mass spectrometry (MS) is the quantitative detection of small amounts of proteins, biomarkers, or pharmacological compounds, even at low concentrations. Researchers have been able to identify the pharmacokinetic characteristics of medications given in microdoses. This safeguards the patient from the medicine's potential side effects while also allowing scientists to figure out what happens to the drug metabolomics in the body. The tiny sample and concentration requirements for the clinical mass spectrometry made it easier to obtain information particular to paediatric patients, who cannot always offer a large enough sample for standard analysis methods